Resource of Asian Primary Immunodeficiency Diseases (RAPID) is a web-based compendium of molecular alterations in primary immunodeficiency diseases. Detailed information about genes and proteins that are affected in primary deficiency diseases is presented along with other pertinent information about protein-protein interactions, microarray gene expression profiles in various organs and cells of the immune system and mouse studies. RAPID also hosts a tool, the mutation viewer, to predict deleterious and novel mutations and also to visualize the mutation positions on the DNA sequence, protein sequence and three-dimensional structure for PID genes. The information in this database should be useful to researchers as well as clinicians.
PIDJ Network
In an effort to elucidate the pathogenesis of PIDs and establish methods of early diagnosis and find effective treatments, RCAI formed a collaboration in 2006 with 13 universities/colleges in Japan which belong to the research team for Investigative Research on Primary Immunodeficiency Disease Syndrome, ("Ministry of Health, Labor and Welfare Survey Research Team").
Keerthikumar, S., Raju, R., Kandasamy, K., Hijikata, A., Ramabadran, S., Balakrishnan, L., Ahmed, M., Rani, S., Selvan, L. N., Somanathan, D. S., Ray, S., Bhattacharjee, M., Gollapudi, S., Ramachandra, Y. L., Bhadra, S., Bhattacharyya, C., Imai, K., Nonoyama, S., Kanegane, H., Miyawaki, T., Pandey, A., Ohara, O. and Mohan, S. 2009. RAPID: Resource of Asian Primary Immunodeficiency Diseases. Nucleic Acids Research. 37, D863-D867.
[PubMed]
Statistics
No of PID Genes
188
No of Mutations
4666
Genes having Mutations
175
No of PubMed Citations
1418
Latest publication
"Prediction of Candidate Primary Immunodeficiency Disease Genes Using a Support Vector Machine Learning Approach" published in October 2009 issue of DNA Research (PMID: 19801557)
Symposium for PID in Asia
The second Asia-Pacific Symposium on Primary Immunodeficiency Diseases is scheduled to be held on February 4th and 5th, 2010 in Chiba, Japan.More..
The first Asia-Pacific Symposium on Primary Immunodeficiency Diseases was held on the 11th and 12th of December 2008 at RIKEN Yokohama Institute, Japan.
More..
RIKEN Jeffrey Modell diagnostic and research center for PID was inaugurated in RIKEN Tokyo office on the 15th January, 2008. The main focus of this center is to establish an information network among PID physicians thereby linking clinical, genetic and immunological information to enable prompt and accurate diagnosis of PIDs.
PIDJ Steering meeting
The first PIDJ Steering meeting took place at RCAI, RIKEN Yokohama Institute on February 27, 2008. Physicians from 13 different Universities across Japan participated in the meeting.
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Resource of Asian Primary Immunodeficiency Diseases (RAPID) is a web-based compendium of molecular alterations in primary immunodeficiency diseases. Detailed information about genes and proteins that are affected in primary deficiency diseases is presented along with other pertinent information about protein-protein interactions, microarray gene expression profiles in various organs and cells of the immune system and mouse studies. RAPID also hosts a tool, the mutation viewer, to predict deleterious and novel mutations and also to visualize the mutation positions on the DNA sequence, protein sequence and three-dimensional structure for PID genes. The information in this database should be useful to researchers as well as clinicians.
